Indy's (Bibi) slimy adventure continues as a mysterious slime stone with magical powers suddenly appears from outer space. When the evil Xenia Kobalt takes hold of the stone the entire world bursts into a fight. Indy, the happy alien Klatu and slime friends both new and old have to go to the impossible to stop Xenia.
Rutger and Thomas are at their wits' end when their beloved dog Paco is suddenly kidnapped in a flying doghouse. Everyone thinks they did it themselves, but the mean Tiffy Woefels is behind it: she wants to make Paco a big star. Rutger and Thomas must prove that they are innocent and save Paco! They get help from an unexpected corner and go on an exciting and hilarious adventure full of action, friendship and barking heroes.
Something terrible happens: an important slime ingredient is running out, which renders slime making impossible for the whole world! Indy sets out to find the origin of this slimy ingredient. She travels the world with her old and new slime friends and they are faced with a slimy mystery. Can Indy get the slime back?