Old Nat Moyer is a talker, a philosopher, and a troublemaker with a fanciful imagination. His companion is Midge Carter, who is half-blind, but still the super of an apartment house. When he is threatened with retirement, Nat battles on his behalf. Nat also takes on his daughter, a drug dealer, and a mugger in this appealing version of a really 'odd couple'.
A pregnant New York social worker begins to develop romantic feelings for her gay best friend, and decides she'd rather raise her child with him, much to the dismay of her overbearing boyfriend.
At the beginning of a nightly Alcoholics Anonymous meeting, Jim seems particularly troubled. His sponsor encourages him to talk that night, the first time in seven months, so he does - and leaves the meeting right after. As Jim wanders the night, searching for some solace in his old stomping grounds, bars and parks where he bought drugs, the meeting goes on, and we hear the stories of survivors and addicts - some, like Louis, who claim to have wandered in looking for choir practice, who don't call themselves alcoholic, and others, like Joseph, whose drinking almost caused the death of his child - as they talk about their lives at the meeting
As lawyer and power broker Roy Cohn lies dying of AIDS in a private hospital room, ghosts from his past visit him as he reflects on his life and loves.
After his mistress runs over a black teen, a Wall Street hotshot sees his life unravel in the spotlight; A down-and-out reporter breaks the story and opportunists clamber to use it to their advantage.
A nice guy has just moved to New York and discovers that he must share his run-down apartment with a couple thousand singing, dancing cockroaches.