Like most of the people in her town, Karen Silkwood works at the local nuclear plant producing highly radioactive plutonium. Exposed one day to a lethal dose of radiation, Karen faces the blank walls of corporate indifference and denial. As her illness increases, her protest grows louder and she becomes an obvious danger to the powers that be.
Morgan and his friends are on a hunting trip on a remote Canadian island when they are attacked by a swarm of giant wasps. Looking for help, Morgan stumbles across a barn inhabited by an enormous killer chicken. After doing some exploring, they discover the entire island is crawling with animals that have somehow grown to giant size. The most dangerous of all of these, however, are the rats, who are mobilizing to do battle with the human intruders.
Zeb Macahan, a pioneering westerner, helps move his brother's family to the wild west. They run into several obstacles including the breakout of the Civil War. This sends the father back to fight in the war and leaves the family to move on ahead.